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Impact of pterygium on the ocular surface and meibomian glands


Autoři: Ana Claudia Viana Wanzeler aff001;  Italo Antunes França Barbosa aff001;  Bruna Duarte aff001;  Eduardo Buzolin Barbosa aff001;  Daniel Almeida Borges aff001;  Monica Alves aff001
Působiště autorů: Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas—UNICAMP, Campinas, SP, Brazil aff001;  Pontific Catholic University of Campinas–PUCCAMP, Campinas, SP, Brazil aff002
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0213956

Souhrn

Purpose

To analyze how ocular surface parameters correlate to presence of pterygium and investigate the possible impact of pterygia on tear film findings and meibomian glands findings.

Methods

We investigated objective parameters of the ocular surface such as conjunctival hyperemia, tear film stability and volume, meibomian gland dysfunction, dry eye disease, corneal topography comparing healthy individuals and correlating with the pterygium clinical presentation.

Results

A total of 83 patients were included. Corneal astigmatism induction was 2.65 ± 2.52 D (0.4–11.8). The impact of pterygium on the ocular surface parameters compared to matched controls was seen in: conjunctival hyperemia (control 1.55±0.39/pterygium 2.14±0.69; p = 0.0001), tear meniscus height (control 0.24±0.05 mm/pterygium 0.36±0.14mm; p 0.0002), meiboscore lower eyelid (control 0.29±0.64/pterygium 1.38±0.95; p 0.0001) and meiboscore upper eyelid (control 0.53±0.62/pterygium 0.98±0.75; p = 0.0083). We found a high number of pterygium patients (88%) presented meibomian gland alterations. Interestingly, meibomian gland loss was coincident to the localization of the pterygium in 54% of the upper and 77% lower lids.

Conclusion

Pterygium greatly impacts on ocular surface by inducing direct alterations in the pattern of meibomian glands besides corneal irregularities, conjunctival hyperemia and lacrimal film alterations, inducing significant symptoms and potential signs of dysfunction.

Klíčová slova:

Biology and life sciences – Anatomy – Cornea – Integumentary system – Skin – Eyelids – Head – Neuroscience – Sensory perception – Vision – Visual acuity – Psychology – Medicine and health sciences – Ocular system – Ocular anatomy – Eyes – Ophthalmology – Eye diseases – Inflammatory diseases – Social sciences


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