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Diagnostic performance and image quality of iterative model-based reconstruction of coronary CT angiography using 100 kVp for heavily calcified coronary vessels


Autoři: Junwoo Kim aff001;  Bon Seung Goo aff001;  Young-Seok Cho aff002;  Tae-Jin Youn aff002;  Dong Jun Choi aff001;  Amar Dhanantwari aff003;  Mani Vembar aff003;  Eun Ju Chun aff001
Působiště autorů: Department of Radiology, Seoul National University Bundang Hospital, Sungnam, Korea aff001;  Department of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, Korea aff002;  CT/AMI Clinical Science, Philips Healthcare, Highland Heights, OH, United States of America aff003
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222315

Souhrn

Objectives

To evaluate the diagnostic performance and image quality of an iterative model-based reconstruction (IMR) using a 100-kVp protocol for the assessment of heavily calcified coronary vessels, compared to those of filtered back projection (FBP) and hybrid iterative technique (iDose4), and also compared to those of IMR with standard 120 kVp protocol.

Methods

Among patients with Agatston scores ≥ 400 who had undergone both coronary CT angiography (CCTA) and invasive coronary angiography (ICA), age- and sex-matched patients with body mass index < 30 were retrospectively enrolled from CCTA with low-kVp protocol (100 kVp, n = 30) and with standard-kVp protocol (120 kVp, n = 30). Image data were all reconstructed with FBP, iDose4, and IMR. In each dataset, the objective and subjective image quality, and diagnostic accuracy (> 50% in luminal reduction as compared with ICA) were assessed.

Results

IMR showed better objective and subjective image quality than FBP and iDose4 in both 100 kVp and 120 kVp groups (all p < 0.05). IMR showed a significantly improved all diagnostic performance compared with FBP (p < 0.05). Compared with iDose4, IMR significantly improved positive predictive value (85.0% vs. 80.5%; p < 0.05). There was no significant difference in image quality and diagnostic performance using IMR between the 100 kVp and 120 kVp groups.

Conclusions

100 kVp IMR may be useful for the assessment of heavily calcified coronary vessels, providing better diagnostic performance than FBP or iDose4 at the same dose, while maintaining similar diagnostic accuracy to 120 kVp IMR.

Klíčová slova:

Research and analysis methods – Imaging techniques – Medicine and health sciences – Vascular medicine – Coronary heart disease – Cardiology – Diagnostic medicine – Diagnostic radiology – Pulmonary imaging – Tomography – Computed axial tomography – Signs and symptoms – Stenosis – Radiology and imaging – Cardiovascular anatomy – Blood vessels – Arteries – Coronary arteries – Aorta – Pathology and laboratory medicine – Biology and life sciences – Neuroscience – Neuroimaging – Anatomy


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