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Deactivation of somatosensory and visual cortices during vestibular stimulation is associated with older age and poorer balance


Autoři: Fatemeh Noohi aff001;  Catherine Kinnaird aff003;  Yiri De Dios aff004;  Igor Kofman aff004;  Scott J. Wood aff005;  Jacob J. Bloomberg aff005;  Ajitkumar P. Mulavara aff004;  Kathleen H. Sienko aff003;  Thad A. Polk aff002;  Rachael D. Seidler aff006
Působiště autorů: Department of Kinesiology, University of Michigan, Ann Arbor, MI, United States of America aff001;  Department of Psychology, University of Michigan, Ann Arbor, MI, United States of America aff002;  Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America aff003;  KBRwyle, Houston, TX, United States of America aff004;  NASA Johnson Space Center, Houston, TX, United States of America aff005;  Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America aff006
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0221954

Souhrn

Aging is associated with peripheral and central declines in vestibular processing and postural control. Here we used functional MRI to investigate age differences in neural vestibular representations in response to pneumatic tap stimulation. We also measured the amount of body sway in multiple balance tasks outside of the MRI scanner to assess the relationship between individuals’ balance ability and their vestibular neural response. We found a general pattern of activation in canonical vestibular cortex and deactivation in cross modal sensory regions in response to vestibular stimulation. We found that activation amplitude of the vestibular cortex was correlated with age, with younger individuals exhibiting higher activation. Deactivation of visual and somatosensory regions increased with age and was associated with poorer balance. The results demonstrate that brain activations and deactivations in response to vestibular stimuli are correlated with balance, and the pattern of these correlations varies with age. The findings also suggest that older adults exhibit less sensitivity to vestibular stimuli, and may compensate by differentially reweighting visual and somatosensory processes.

Klíčová slova:

People and places – Population groupings – Age groups – Elderly – Young adults – Biology and life sciences – Neuroscience – Sensory perception – Vision – Brain mapping – Functional magnetic resonance imaging – Neuroimaging – Cognitive science – Cognitive neuroscience – Motor reactions – Postural control – Psychology – Physiology – Biological locomotion – Gait analysis – Social sciences – Medicine and health sciences – Diagnostic medicine – Diagnostic radiology – Magnetic resonance imaging – Radiology and imaging – Research and analysis methods – Imaging techniques – Physical sciences – Mathematics – Geometry – Ellipses


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