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Transfusion and Haematology Today

Management of major surgery in patients with haemophilia A using continuous infusion vs. bolus injections of FVIII – a pharmacokinetic approach to treatment

Management of major surgery in patients with haemophilia A using continuous infusion vs. bolus injections of FVIII – a pharmacokinetic approach to treatment

Management of major surgery represents the most challenging issue of replacement therapy in severe haemophilia. The aim of our open, prospective, nonrandomised study was to...

Full article   Transfusion and Haematology Today Issue: 2/2017

Specialization: Haematology Internal medicine Clinical oncology
Interferon alpha in the treatment of Philadelphia-negative myeloproliferative neoplasms

Interferon alpha in the treatment of Philadelphia-negative myeloproliferative neoplasms

Introduction: Interferon alfa (IFN-α) has been used for over 30 years to treat myeloproliferative neoplasms. Recombinant IFN-α (rIFN-α) and pegylated IFN-α (Peg-IFN-α) have...

Full article   Transfusion and Haematology Today Issue: 2/2017

Specialization: Haematology Internal medicine Clinical oncology
Prevention and therapy of venous thromboembolism in cancer patients

Prevention and therapy of venous thromboembolism in cancer patients

Symptomatic venous thromboembolism occurs 4–7 times more frequently in cancer patients as compared to non-cancer patients. This is due to many factors related to the tumour...

Full article   Transfusion and Haematology Today Issue: 1/2017

Specialization: Clinical oncology Internal medicine Haematology
Modern therapy of acute myeloid leukaemia

Modern therapy of acute myeloid leukaemia

Acute myeloid leukaemia is a clonal malignant disease affecting mainly elderly patients. This previously nearly always fatal disease is now curable in 35–40 % of younger...

Full article   Transfusion and Haematology Today Issue: 1/2017

Specialization: Clinical oncology Internal medicine Haematology
Experience with ruxolitinib in the treatment of myelofibrosis and polycythaemia vera at Czech haematological institutions

Experience with ruxolitinib in the treatment of myelofibrosis and polycythaemia vera at Czech haematological institutions

Backgrounds: Ruxolitinib, a Janus kinase 1 and 2 inhibitor, demonstrated efficacy in patients with myelofibrosis and polycythaemia vera in the randomized COMFORT-I, COMFORT-II...

Full article   Transfusion and Haematology Today Issue: 1/2017

Specialization: Haematology Internal medicine Clinical oncology
Autoimmune haemolytic anaemia – diagnosis and treatment, including erythrocyte transfusions

Autoimmune haemolytic anaemia – diagnosis and treatment, including erythrocyte transfusions

Diagnosis of autoimmune haemolytic anaemia (AIHA) is usually quite straightforward. It is based on the clinical and laboratory presentation of haemolytic anaemia and serological...

Full article   Transfusion and Haematology Today Issue: 1/2017

Specialization: Haematology Internal medicine Clinical oncology
Stability of complete blood count and microscopic differential count parameters

Stability of complete blood count and microscopic differential count parameters

Introduction: Complete blood count (CBC) including the automated differential white blood cell count (WBC differential) represent a routine laboratory test. The time interval...

Full article   Transfusion and Haematology Today Issue: 4/2016

Specialization: Haematology Internal medicine Clinical oncology
Low-dose computed tomography of the skeleton in multiple myeloma staging

Low-dose computed tomography of the skeleton in multiple myeloma staging

The objective of imaging in plasma cell dyscrasia staging is the detection of osteolytic bone lesions and associated soft tissue masses. In 2012, we initiated a project...

Full article   Transfusion and Haematology Today Issue: 4/2016

Specialization: Clinical oncology Internal medicine Haematology
Apheresis platelets versus pooled platelets – comparison of quality and safety

Apheresis platelets versus pooled platelets – comparison of quality and safety

Platelet transfusions have an important place in haemotherapy thanks to the progress in oncological and intensive care treatment. Apheresis platelets as well as pooled platelets...

Full article   Transfusion and Haematology Today Issue: 4/2016

Specialization: Clinical oncology Internal medicine Haematology
The monoclonal antibody daratumumab in the treatment of multiple myeloma

The monoclonal antibody daratumumab in the treatment of multiple myeloma

The monoclonal antibody daratumumab is a new and effective drug for the treatment of multiple myeloma. Results of clinical trials have demonstrated a high efficacy in...

Full article   Transfusion and Haematology Today Issue: 4/2016

Specialization: Clinical oncology Internal medicine Haematology
 

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