Paliperidone palmitate (PP) is a novel long-acting injectable antipsychotic registered for maintenance treatment of schizophrenia. Paliperidone is an active metabolite of...

Authors: Doc. MUDr. Pavel Mohr, Ph.D.
Issue: 6/2011

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Neuropathic pain develops as a result of lesions or disease affecting the somatosensory nervous system either in the periphery or centrally. It constitutes a heterogeneous group...

Authors: Prof. MUDr. Zdeněk Ambler, DrSc.
Issue: 6/2011

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Multiple sclerosis is an inflammatory process in the central nervous system involving autoimmune mechanisms, manifesting as neurodegenerative consequences associated with...

Authors: Prof. MUDr. Eva Havrdová, CSc.
Issue: 6/2011

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Anakinra acts as an interleukin-1 receptor antagonist, and blocks this key inflammation mediator. In combination with methotrexate, the substance has been approved for use in...

Authors: Prof. MUDr. Anna Šedivá, DSc.; MUDr. Jiří Slíva, Ph.D.; doc. MUDr. Pavla Doležalová, CSc.; MUDr. Martina Skácelová
Issue: 6/2011

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Pain is constant manifestation of osteoarthritis (OA) and the key factor limiting function and patient quality of life. Symptomatic therapy of OA is therefore the foundation of...

Authors: MUDr. Martina Olejárová, CSc.
Issue: 6/2011

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