Changes of the laboratory indicators of hemostasis in hepatopathy
Authors: R. Hrabcová, P. Kessler, J. Gumulec, M. Kouri
Authors - sphere of activity: 1Ústav klinické hematologie FN Ostrava, přednosta prim. MUDr. Jaromír Gumulec
,
2Oddělení hematologie a transfuziologie Nemocnice Pelhřimov, p.o., přednosta prim. MUDr. Petr Kessler
,
3BioMerieux, South Africa, general manager Marcin Kouri,
4SPADIA LAB a.s., Česká republika, ředitel RNDr. Martin Radina
Article: Vnitř Lék, 2010, 56(Supplementum 1): 120-122
Category: 16th Parizek's Days, Ostrava-Poruba, March 25th –26th 2010
Number of articles displayed: 333x
Summary
The liver has a central role in hemostasis. It is the major site of synthesis of the coagulation factors, inhibitors and components of fibrinolytic system. The liver also functions as a site for clearance of their activated forms from the circulation. Liver disease leads to a shift in the delicately controlled hemostatic system in both primary and secondary hemostasis.
Key words:
liver disease – thrombocytopenia – platelet dysfunction – coagulation abnormalities – DIC
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