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Epidemiology, Microbiology, Immunology

Identification of bacteria from blood cultures by fluorescence in situ hybridization

Identification of bacteria from blood cultures by fluorescence in situ hybridization

The diagnosis of bacterial agents of sepsis from blood cultures is crucial for the subsequent treatment of this condition. The aim of this study was to compare Gram stain...

Full article   Epidemiology, Microbiology, Immunology Issue: 2/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Virulence and antibiotic resistance genes in Campylobacter spp. in the Czech Republic

Virulence and antibiotic resistance genes in Campylobacter spp. in the Czech Republic

Objective: Thermotolerant species of the genus Campy-lobacter are the important agents causing human foodborne infections throughout the world. The aims of this study were to...

Full article   Epidemiology, Microbiology, Immunology Issue: 2/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
The effect of adenotomy, allergy and smoking on microbial colonization of upper aerodigestive tract in children

The effect of adenotomy, allergy and smoking on microbial colonization of upper aerodigestive tract in children

Aim: To evaluate microbial colonization of upper aerodigestive tract in children and to investigate the influence of adenoid hypertrophy, allergy and exposition to cigarette...

Full article   Epidemiology, Microbiology, Immunology Issue: 2/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Sepsis-related mortality in the Czech Republic: multiple causes of death analysis

Sepsis-related mortality in the Czech Republic: multiple causes of death analysis

Aim: Sepsis represents an increasingly frequent complication in the survival of the hospitalized persons. The nation-wide burden of the sepsis-related mortality in the Czech...

Full article   Epidemiology, Microbiology, Immunology Issue: 2/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Diagnostic relevance of the chemokine CXCL13 and anti-C6 peptide antibodies in patients with neuroborreliosis

Diagnostic relevance of the chemokine CXCL13 and anti-C6 peptide antibodies in patients with neuroborreliosis

Aim of the study: The study was focused on testing the diagnostic value of detection of the chemokine CXCL13 (B lymphocyte chemoattractant) and anti-C6 peptide (synthetic...

Full article   Epidemiology, Microbiology, Immunology Issue: 2/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
The prevalence of antibodies against Hepatitis E Virus in the Czech Republic: serological survey

The prevalence of antibodies against Hepatitis E Virus in the Czech Republic: serological survey

Aim: To determine the prevalence of antibodies against hepatitis E virus in the general population of the Czech Republic of age 15 to 64, to analyse the age and sex distribution...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Medical virology Hygiene and epidemiology Clinical microbiology
Infectious diseases and laboratory diagnosis
in the Terezin Jewish Ghetto

Infectious diseases and laboratory diagnosis
in the Terezin Jewish Ghetto

The article is a historical review study which deals with the epidemiological situation in the Terezin Jewish Ghetto, including the possibilities for laboratory diagnosis and...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Non-specific immunotherapy inhibits angiogenesis – results of the monitoring 
of serum levels of vascular endothelial growth factor and matrix metalloproteinase 8 in patients with malignant 
melanoma receiving adjuvant high-dose interferon therapy

Non-specific immunotherapy inhibits angiogenesis – results of the monitoring 
of serum levels of vascular endothelial growth factor and matrix metalloproteinase 8 in patients with malignant 
melanoma receiving adjuvant high-dose interferon therapy

Objective: Interestingly, evidence is currently emerging that the activation of angiogenesis leads to immunomodulatory/immunosuppressive effects both at the local and systemic...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Clinical microbiology Medical virology Hygiene and epidemiology
Foodborne botulism – 
a re-emerging public health challenge

Foodborne botulism – 
a re-emerging public health challenge

Human foodborne botulism is an intoxication caused by ingestion of botulinum neurotoxins (BoNT) of serotypes A, B, E, and rarely also serotype F, produced in contaminated food...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
The possibilities for the implementation
 of whole genome sequencing (WGS) of Neisseria meningitidis in molecular surveillance of invasive meningococcal disease in the Czech Republic

The possibilities for the implementation
 of whole genome sequencing (WGS) of Neisseria meningitidis in molecular surveillance of invasive meningococcal disease in the Czech Republic

The implementation of the surveillance of invasive meningococcal disease is recommended worldwide. The Whole Genome Sequencing (WGS) method increasingly comes to the fore, which...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Clinical microbiology Medical virology Hygiene and epidemiology