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Epidemiology, Microbiology, Immunology

Trend and challenge in mother-to-child transmission of syphilis

Trend and challenge in mother-to-child transmission of syphilis

Objective: The aim of the study was to evaluate the epidemiological trends in the incidence rates of mother-to-child transmission of syphilis, syphilis in women of reproductive...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Foodborne botulism – 
a re-emerging public health challenge

Foodborne botulism – 
a re-emerging public health challenge

Human foodborne botulism is an intoxication caused by ingestion of botulinum neurotoxins (BoNT) of serotypes A, B, E, and rarely also serotype F, produced in contaminated food...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
The possibilities for the implementation
 of whole genome sequencing (WGS) of Neisseria meningitidis in molecular surveillance of invasive meningococcal disease in the Czech Republic

The possibilities for the implementation
 of whole genome sequencing (WGS) of Neisseria meningitidis in molecular surveillance of invasive meningococcal disease in the Czech Republic

The implementation of the surveillance of invasive meningococcal disease is recommended worldwide. The Whole Genome Sequencing (WGS) method increasingly comes to the fore, which...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
The prevalence of antibodies against Hepatitis E Virus in the Czech Republic: serological survey

The prevalence of antibodies against Hepatitis E Virus in the Czech Republic: serological survey

Aim: To determine the prevalence of antibodies against hepatitis E virus in the general population of the Czech Republic of age 15 to 64, to analyse the age and sex distribution...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Clinical microbiology Hygiene and epidemiology Medical virology
Infectious diseases and laboratory diagnosis
in the Terezin Jewish Ghetto

Infectious diseases and laboratory diagnosis
in the Terezin Jewish Ghetto

The article is a historical review study which deals with the epidemiological situation in the Terezin Jewish Ghetto, including the possibilities for laboratory diagnosis and...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Non-specific immunotherapy inhibits angiogenesis – results of the monitoring 
of serum levels of vascular endothelial growth factor and matrix metalloproteinase 8 in patients with malignant 
melanoma receiving adjuvant high-dose interferon therapy

Non-specific immunotherapy inhibits angiogenesis – results of the monitoring 
of serum levels of vascular endothelial growth factor and matrix metalloproteinase 8 in patients with malignant 
melanoma receiving adjuvant high-dose interferon therapy

Objective: Interestingly, evidence is currently emerging that the activation of angiogenesis leads to immunomodulatory/immunosuppressive effects both at the local and systemic...

Full article   Epidemiology, Microbiology, Immunology Issue: 1/2017

Specialization: Clinical microbiology Medical virology Hygiene and epidemiology
The incidence, mortality and risk factors of prostate cancer

The incidence, mortality and risk factors of prostate cancer

Prostate cancer is a serious oncological disease in males. There has been a significant escalation in the incidence of this malignancy in the Czech Republic and in developed...

Full article   Epidemiology, Microbiology, Immunology Issue: 4/2016

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Epidemiological 
significance of the metabolic syndrome

Epidemiological 
significance of the metabolic syndrome

From an epidemiological point of view, the metabolic syndrome is a group of risk factors causally, rather than coincidentally, related to insulin resistance. The metabolic...

Full article   Epidemiology, Microbiology, Immunology Issue: 4/2016

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
Differential diagnosis of the viral etiology of suspected mumps in a population with high vaccine coverage

Differential diagnosis of the viral etiology of suspected mumps in a population with high vaccine coverage

Aim: In this study, buccal swabs from patients with the clinical picture of parotitis epidemica in whom mumps virus (MV) infection was not confirmed by direct detection or...

Full article   Epidemiology, Microbiology, Immunology Issue: 4/2016

Specialization: Hygiene and epidemiology Medical virology Clinical microbiology
IGRA methods in the routine operation – QuantiFERON<sup>®</sup>-TB Gold or T-SPOT.TB?

IGRA methods in the routine operation – QuantiFERON®-TB Gold or T-SPOT.TB?

For indirect diagnosis of tuberculosis, two commercial IGRA (Interferon Gamma Release Assay) assays are available – primal QuantiFERON®-TB Gold test, new version QuantiFERON...

Full article   Epidemiology, Microbiology, Immunology Issue: 4/2016

Specialization: Clinical microbiology Hygiene and epidemiology Medical virology