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Protein concentration in human milk after preterm delivery


Authors: I. Burianová 1,4;  J. Malý 2;  M. Navratilova 2;  E. Tichá 2;  V. Vítková 1,3;  J. Kudláčková 1;  B. Zlatohlávková 5;  E. Vokurková 5;  K. Boráková 6;  T. Brožová 6;  M. Pánek 7;  J. Pánková 7;  L. Kantor 8;  I. Vránová 8;  J. Bronský 4
Authors‘ workplace: Novorozenecké oddělení s JIP, Thomayerova nemocnice, Praha 1;  Dětská klinika LF UK a FN, Hradec Králové 2;  Ústav patologické fyziologie 1. LF UK, Praha 3;  Pediatrická klinika 2. LF UK a FN Motol, Praha 4;  Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha 5;  Ústav péče o matku a dítě, Praha 6;  Novorozenecké oddělení, Krajská zdravotní a. s., Ústí nad Labem 7;  Novorozenecké oddělení FN, Olomouc 8
Published in: Čes-slov Pediat 2017; 72 (8): 472-477.
Category: Original Papers

Overview

Aim of study:
To evaluate the amount of protein in a set of human milk samples using mid-infrared human milk analyser after preterm labour during the first two months of lactation.

Methods:
Analysis of the donated milk samples between 24+0 and 35+6 gestational age (GA) was designed as prospective observational cohort trial. Two milk samples were analysed up to the discharge from the hospital, week 9 or loss of lactation. Analysis was performed using the MIRIS Human Milk Analyser (MIRIS AB, Uppsala, Sweden).

Results:
Total of 1917 human milk samples donated by 225 mothers after preterm labour were analysed. Group A (24–30 GA) contained 969 milk samples, the group B (31–35 GA) contained 948 milk samples. Mean true protein content decreased from 1.72 g/dL in group A and 1.65 g/dL in group B at the end of the first week of life to 1.1 g/dL in both groups at the end of the week 3, and remained stable with mean values around 1.0 g/dL up to week 9.

Conclusion:
There was no difference in the protein content of human milk as a function of term of premature delivery. Moreover the protein content was lower than expected and even decreased during first three weeks of lactation. We did not detect a significant difference in milk protein levels between group A (24–30 GA) and group B (31–35 GA).

Key words:
human milk, macronutrients, protein, premature birth


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Neonatology Paediatrics General practitioner for children and adolescents
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