Multiple myeloma, a plasma cell malignancy, still remains a hard-to-treat hematological disease that desperately needs new therapy targeting plasmocytes but also the bone marrow...

Authors: Kubiczková L., Matějíková J., Sedlaříková L., Kryukov F., Hájek R., Ševčíková S.
Issue: 1/2013

Read article

Background: Primary intracranial germ cell tumors represent a rare category of neoplasms, which occur in children and young adults. The WHO classification divides intracranial...

Authors: Miškovská V., Usakova V., Vertakova-Krakovska B., Mrinakova B., Lehotská V., Chorváth M., Rychlý B., 
Steno J., Ondruš D.
Issue: 1/2013

Read article

Background:Targeted biological therapy based on blocking growth factor receptors and inhibition of cancer-inducing signaling pathways is a new treatment facility for patients...

Authors: Robešová B., Bajerová M., Vašíková A., Ostřížková L., Hausnerová J., Kyclová J., Pospíšilová Š., 
Mayer J., Dvořáková D.
Issue: 1/2013

Read article

Background:Malignant melanoma is considered to be highly resistant to chemotherapy, radiotherapy, hormonotherapy and standard immunotherapy (interleukin 2, interferon alpha...

Authors: Bílek O., Tuček Š., Veselý K., Fabian P., Robešová B., Adámková Krákorová D., Lakomý R., Svoboda M., 
Jurečková A., Halámková J., Králová J., Šikulíncová L., Podhorec J., Tomášek J., Kiss I., Vyzula R.
Issue: 1/2013

Read article

Background:Spontaneous hepatic bleeding is a rare but potentially life-threatening complication of primary systemic amyloidosis. Although the liver is a common site of amyloid...

Authors: Szturz P., Kyclová J., Moulis M., Navrátil M., Adam Z., Vaníček J., Mayer J.
Issue: 1/2013

Read article