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Clinical biochemistry and metabolism

Comparison of Measurement Free Light Chains by SPA<sub>PLUS</sub> and Immage 80

Comparison of Measurement Free Light Chains by SPAPLUS and Immage 80

Objective: Comparison of turbidimetric measurement of FLC concentrations by SpaPLUS (The Binding Site) and Immage 800 (Beckman Coulter), including index κ/λ, was the aim of...

Full article   Clinical Biochemistry and Metabolism Issue: 3/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
Congenital disorders of glycosylation: alpha-dystroglycanopathies

Congenital disorders of glycosylation: alpha-dystroglycanopathies

Alpha-dystroglycanopathies are rare inherited diseases that belong to the group of congenital disorders of glycosylation, and due to their clinical symptoms they also fall into...

Full article   Clinical Biochemistry and Metabolism Issue: 3/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
Therapeutic monoclonal antibodies in clinical laboratory

Therapeutic monoclonal antibodies in clinical laboratory

Monoclonal antibody therapy is a form of immunotherapy that uses monoclonal antibodies to bind monospecifically to certain proteins or cells. This may then stimulate the patient...

Full article   Clinical Biochemistry and Metabolism Issue: 3/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
Determination of albumin in serum and plasma. Harmonization of results and clinical recommendations in patients with renal diseases.

Determination of albumin in serum and plasma. Harmonization of results and clinical recommendations in patients with renal diseases.

Our presentation deals namely with degree of harmonization of results in serum/plasma albumin measurement. We describe differences between BCG and BCP methods and between serum...

Full article   Clinical Biochemistry and Metabolism Issue: 3/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
Interpretation difficulties in electrophoresis and immunofixation findings in patients with multiple myeloma after autologous transplantation

Interpretation difficulties in electrophoresis and immunofixation findings in patients with multiple myeloma after autologous transplantation

Objective: The study of abnormal gradients including new monoclonal immunoglobulins and oligoclonal bands in patients with multiple myeloma after autologous...

Full article   Clinical Biochemistry and Metabolism Issue: 2/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
External quality evaluation programs at the time of harmonizing laboratory results

External quality evaluation programs at the time of harmonizing laboratory results

Objective: Principles of assessment for standardized laboratory methods in contemporary EQA programs in era harmonizationMethod: Publication on the ways of using control limits...

Full article   Clinical Biochemistry and Metabolism Issue: 2/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
Laboratory aspects of systemic AA amyloidosis

Laboratory aspects of systemic AA amyloidosis

The aim of the communication is to remind the issue and the clinical significance of selected laboratory parameters used in the diagnosis and monitoring of patients with AA...

Full article   Clinical Biochemistry and Metabolism Issue: 2/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
MedPed project in Czech Republic

MedPed project in Czech Republic

Familial hypercholesterolemia (FH) is the most serious type of hereditary dyslipidemia. Patients with FH may develop cardiovascular event (primarily heart attack) in young age...

Full article   Clinical Biochemistry and Metabolism Issue: 2/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist
23 cases of Metformin-induced Metabolic Lactic Acidosis in Patients treated with Metformin

23 cases of Metformin-induced Metabolic Lactic Acidosis in Patients treated with Metformin

Metformin is currently the cornerstone of treatment of Type-2 diabetes mellitus with obesity (DM2). Its most serious side effect is metabolic acidosis referred to as metformin...

Full article   Clinical Biochemistry and Metabolism Issue: 2/2017

Specialization: Clinical biochemistry Nuclear medicine Nutritive therapist