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Clinico-pathological characteristics and outcomes of patients with biopsy-proven hypertensive nephrosclerosis: a retrospective cohort study

Clinico-pathological characteristics and outcomes of patients with biopsy-proven hypertensive nephrosclerosis: a retrospective cohort study

Background: This study aimed to investigate renal outcomes and their predictors in biopsy-proven hypertensive nephrosclerosis (HN) patients and to compare clinico-pathological...

Full article   BMC Nephrology Issue: 42/2016

Specialization: Paediatric nephrology Nephrology
Renal disease and accidental falls: a review of published evidence

Renal disease and accidental falls: a review of published evidence

Background: The pathogenesis of falling is complex, and identification of risk factors may be essential for prevention. The relationship between renal disease and falls is...

Full article   BMC Nephrology Issue: 176/2015

Specialization: Paediatric nephrology Nephrology
Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1

Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1

Background: IgA nephropathy (IgAN) is the most common glomerulonephritis in the world, affecting close to a million people. Circulating galactose-deficient IgA (gd-IgA), present...

Full article   BMC Nephrology Issue: 40/2016

Specialization: Nephrology Paediatric nephrology
Incremental cost-utility of sevelamer relative to calcium carbonate for treatment of hyperphosphatemia among pre-dialysis chronic kidney disease patients

Incremental cost-utility of sevelamer relative to calcium carbonate for treatment of hyperphosphatemia among pre-dialysis chronic kidney disease patients

Background: Sevelamer is an alternative to calcium carbonate for the treatment of hyperphosphatemia among non-dialysis dependent patients with chronic kidney disease (CKD...

Full article   BMC Nephrology Issue: 45/2016

Specialization: Nephrology Paediatric nephrology
Predicting patient survival after deceased donor kidney transplantation using flexible parametric modelling

Predicting patient survival after deceased donor kidney transplantation using flexible parametric modelling

Background: The influence of donor and recipient factors on outcomes following kidney transplantation is commonly analysed using Cox regression models, but this approach is not...

Full article   BMC Nephrology Issue: 51/2016

Specialization: Nephrology Paediatric nephrology
Gas6 protein: its role in cardiovascular calcification

Gas6 protein: its role in cardiovascular calcification

Background: Cardiovascular calcifications can be prevented by vitamin K and are accelerated by vitamin K antagonists. These effects are believed to be mainly mediated by the...

Full article   BMC Nephrology Issue: 52/2016

Specialization: Nephrology Paediatric nephrology
Impaired P2Y12 inhibition by clopidogrel in kidney transplant recipients: results from a cohort study

Impaired P2Y12 inhibition by clopidogrel in kidney transplant recipients: results from a cohort study

Background: Cardiovascular complications represent a major cause of morbidity and mortality for patients who received kidney transplantation (KT). However, the impact of KT and...

Full article   BMC Nephrology Issue: 58/2016

Specialization: Nephrology Paediatric nephrology
Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease – cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort

Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease – cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort

Background: Diabetes mellitus (DM) is the leading cause of end-stage renal disease. Little is known about practice patterns of anti-diabetic therapy in the presence of chronic...

Full article   BMC Nephrology Issue: 59/2016

Specialization: Paediatric nephrology Nephrology Diabetology
Acute pancreatitis associated with everolimus after kidney transplantation: a case report

Acute pancreatitis associated with everolimus after kidney transplantation: a case report

Background: Acute pancreatitis (AP) following KT is a rare and often fatal complication of the early post-transplant period. Common causative factors for AP are rare after KT...

Full article   BMC Nephrology Issue: 163/2016

Specialization: Paediatric nephrology Nephrology
Case report: severe bradycardia, a reversible cause of “Cardio-Renal-Cerebral Syndrome”

Case report: severe bradycardia, a reversible cause of “Cardio-Renal-Cerebral Syndrome”

Background: Cardio-Renal Syndromes were first classified in 2008 and divided into five subtypes. The type 1 Cardio-Renal Syndrome (CRS) is characterized by acute decompensation...

Full article   BMC Nephrology Issue: 162/2016

Specialization: Paediatric nephrology Nephrology
The effect of continuous venovenous hemofiltration on neutrophil gelatinase-associated lipocalin plasma levels in patients with septic acute kidney injury

The effect of continuous venovenous hemofiltration on neutrophil gelatinase-associated lipocalin plasma levels in patients with septic acute kidney injury

Background: It is known that continuous venonenous hemofiltration (CVVH) does not affect the plasma level of neutrophil gelatinase-associated lipocalin (pNGAL) in acute kidney...

Full article   BMC Nephrology Issue: 154/2016

Specialization: Paediatric nephrology Nephrology
Heterozygous p.S811F RET gene mutation associated with renal agenesis, oligomeganephronia and total colonic aganglionosis: a case report

Heterozygous p.S811F RET gene mutation associated with renal agenesis, oligomeganephronia and total colonic aganglionosis: a case report

Background: Several shared common gene networks participate in development of interstinal ganglia and also nephron formation; the glial cell line-derived neurotrophic factor/Ret...

Full article   BMC Nephrology Issue: 146/2016

A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development

A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development

Background: Immunotactoid glomerulopathy (ITG) is a rare cause of proteinuria characterized by organized microtubular deposits in the glomerulus. ITG has been associated with...

Full article   BMC Nephrology Issue: 140/2016

Sudden onset of parathyroid hormone-independent severe hypercalcemia from reversal of tumoral calcinosis in a dialysis patient

Sudden onset of parathyroid hormone-independent severe hypercalcemia from reversal of tumoral calcinosis in a dialysis patient

Background: Tumoral calcinosis is a rare manifestation of extraskeletal calcification, featuring large calcified cystic masses in the periarticular regions of large joints. In...

Full article   BMC Nephrology Issue: 137/2016

A practical approach to low protein diets for patients with chronic kidney disease in Cameroon

A practical approach to low protein diets for patients with chronic kidney disease in Cameroon

Cameroon is a low–middle income country with a rich diversity of culture and cuisine. Chronic kidney disease (CKD) is common in Cameroon and over 80 % of patients present late...

Full article   BMC Nephrology Issue: 126/2016

The possible involvement of intestine-derived IgA<sub>1</sub>: a case of IgA nephropathy associated with Crohn’s disease

The possible involvement of intestine-derived IgA1: a case of IgA nephropathy associated with Crohn’s disease

Background: A link between IgA nephropathy and Crohn’s disease has recently been reported. Other researchers hypothesize that intestine-derived IgA complexes deposit in...

Full article   BMC Nephrology Issue: 122/2016