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Cigarette smoke leads to the production of a large number of different free radicals, especially superoxide, alkoxy- and alkyl- radicals and free hydroxyl radicals. Antioxidant defence must be complex, i.e. a mixture of different substances.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 597x
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Ethics committees in the Czech Republic
Ethics committees are relatively new phenomena in the Czech Republic. From the history of the origin of ethics committees and the development of their roles, it is possible to document the function of certain ethical mechanisms in society.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 367x
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Skin examination by high-frequency ultrasound
The introduction of high frequency ultrasound scanners has made it possible for non-invasive technology to be used in dermatology.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 507x
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Diagnostic problems of non-alcoholic steatohepatitis in clinicopathological practice
Non-alcoholic fatty liver disease (NAFLD) has recently become one of the most frequent and most important hepatic disorders throughout the world. This complex clinicopathological condition includes a spectrum of several nosological entities with distinct prognosis.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 1676x
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Objectives: The aim of this study is to evaluate the significance of nasal bone as a marker for trisomy 21 in the group of women that underwent invasive procedures in our center at 11 to 14 weeks’ gestation.
Source: Czech Gynaecology
Issue: 1 / 2007
Number of articles displayed: 818x
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Objective: To analyse factors which led to the diagnosis of endometrial carcinoma in patients still in asymptomatic stage and to find out if such early diagnosis has an impact on further prognosis of this carcinoma. Design: Retrospective study.
Source: Czech Gynaecology
Issue: 1 / 2007
Number of articles displayed: 279x
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Clinical aspects and neurobiology of vascular dementia
The first book on vascular dementia (VD) is more than 450 years old; nevertheless epidemiology, signs and symptoms, pathogenesis, prevention and therapy of VD are currently discussed more than ever.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 682x
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Febrile infections in travellers returning from the tropics
Travel medicine is a dynamically evolving medical speciality. As the number of Czech tourists travelling to tropical regions is increasing, more and more general practitioners are seeing and treating these patients.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 487x
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Combination of paclitaxel + gemcitabine as a salvage therapy in patients with germ cell tumors.
Roughly 20% of patients with advanced GCT relapse or fail to achieve a complete response to conventional cis-platin based chemotherapy. Patients (pts) with relapsed or refractory GCT may be cured by salvage chemotherapy with gemcitabine and paclitaxel.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 526x
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Causal treatment options for lower extremity varices
By way of introduction, the article reviews the pathophysiology of lower extremity varices and outlines current methods of examination. All the possible treatment options (from minimally invasive therapy to complex stripping) are discussed based on the pathophysiological genesis.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 599x
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The aim of the study is to provide more information about occupational asthma and occupational rhinitis from both the health and also the socio-economic point of view and to emphasize the role of co-operation between general practitioner and specialist for occupational diseases.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 356x
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Smoking Helpline service – an important programme in the fight against tobbaco addition
A “Quitline” is an important part of the spectrum of services provided to help treat tobacco dependence. The Czech Quitline was set up on January the 1st, 2005, and is operated daily between 12pm and 8pm. It is run by specially trained medical students from all three Prague medical schools.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 344x
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Dynamics of oncomarkers duringthe oncological treatment of testicular germinal cell tumours
Testicular germ cell tumours (GCT) are highly curable though require proper management at all stages. GCTs are classified in two major subgroups: seminoma and non-seminoma.
Source: General Practitioner
Issue: 1 / 2008
Number of articles displayed: 572x
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Early cancerogenesis in head and neck squamous cell carcinoma
Squamous cell carcinoma is the most frequent malignant tumour of the head and neck. It affects more than one thousand patients in the Czech Republic each year.
Source: General Practitioner
Issue: 9 / 2008
Number of articles displayed: 2455x
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Preoperative Preparation and Examinations Before Scheduled Cardiosurgical Intervention
In our article we inform about complete preoperative preparation and about required examinations before the scheduled cardiosurgical procedure.
Source: Journal of Czech Physicians
Issue: 1 / 2008
Number of articles displayed: 758x
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Transparent accountability in medicine and responsibility of ethics committees.
This paper is a reflection on the meaning of the term “accountability”, which is connected with the concepts of responsibility, trust and transparency.
Source: General Practitioner
Issue: 2 / 2008
Number of articles displayed: 176x
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Current possibilities and problems of antiretroviral therapy
The introduction of antiretroviral therapy to clinical practice has assured a significant improvement in the quality of life for people living with HIV infection, and has substantially prolonged their life expectancy.
Source: General Practitioner
Issue: 2 / 2008
Number of articles displayed: 221x
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Insights into the pathogenesis of autism spectrum disorders from the molecular and cellular level
Despite the great array of observations, the etiopathogenesis of the autism spectrum disorders (ASD) is poorly defined.
Source: General Practitioner
Issue: 2 / 2008
Number of articles displayed: 201x
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The memory in the human brain is not a unified system.
Source: General Practitioner
Issue: 2 / 2008
Number of articles displayed: 274x
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Metallothionein and its relation to anticancer treatment by platinum complexes
Metallothionein: It is a small protein with high content of cysteine, whose sulfhydryl groups give metallothionein its unique properties.
Source: General Practitioner
Issue: 2 / 2008
Number of articles displayed: 220x
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